Amazon MemoryDB for Redis
Similar to AWS ElastiCache, Amazon MemoryDB for Redis is a database service that is compatible to Redis and Medis supports it out-of-the-box.
If you've set a VPN and you are able to connect to your Amazon MemoryDB for Redis directly from your local machine, all you need to do is to select the "Cluster" mode in Medis and fill the Cluster endpoint that you can find in the Cluster details page in to the Host field.
Find your cluster endpoint
Select "Cluster" mode and make sure SSL is enabled